Heritable Archives - Brein in Action

Obesity is 60% heritable. And this means …

Peter Moleman29/06/2021Articles, Genes and heredityLeave a Comment

The mass media report percentages of heritability. for various conditions. For instance autism is 90% heritable, height 80%, BMI 60%, musical aptitude 50%, depression 40%, breast cancer 30%. But these percentages are of no use to you, because they only apply to the population investigated, not in general. And they vary immensely between populations. Telling someone that their trait or illness has a specific heritability percentage is wrong.

Families, genes, and psychiatric disorders

Peter Moleman10/06/2021Articles, Genes and heredity, PsychiatryLeave a Comment

Genetic variants and mutations can increase the susceptibility to psychiatric disorders. But the DSM does not really apply to the real world of genetically determined presentations. Hospital departments for DSM categories are outdated. Clusters of families would make better units for research into and care for severe mental disorders.

Can you inherit homosexuality?

Peter Moleman31/05/2021Articles, Brain development, Genes and heredityLeave a Comment

I can still remember the commotion which arose in 1990 when Dutch neuroscientist Dick Swaab published an article saying that homosexual men had an area in their hypothalamus which was twice the size of the same area in heterosexual men. Many found the idea – that homosexuality might have a biological basis – quite alarming! At the time I worked … Read More

The new crystal ball: predicting future disease

Peter Moleman03/10/2019Articles, Genes and heredity, PsychiatryLeave a Comment

Disease can be seen as the antechamber of death.
Are there reliable tests for predicting disease? The short answer is: not for Alzheimer’s or other common diseases. Tests do exist for some specific diseases, most with known familial predispositions, such as Huntington’s disease, cystic fibrosis, Duchenne’s dystrophy and many more.

The basis for most of the severe mental disorders is clear

Peter Moleman08/08/2019Articles, Brain development, Psychiatry1 Comment

The basis for most of the severe mental disorders is in your genes and the early development of the brain. But we will not be able to find THE cause of these disorders. Why not?