Is a thought simply the sum total of the activity of all the neurons in the brain? No, just as a message is not simply the placement of a sequence of letters which follow the rules of grammar. How do those letters stand in relation to that message? How does the activity of neurons stand in relation to a thought? Was Descartes right, or are we our brain?
Disease can be seen as the antechamber of death.
Are there reliable tests for predicting disease? The short answer is: not for Alzheimer’s or other common diseases. Tests do exist for some specific diseases, most with known familial predispositions, such as Huntington’s disease, cystic fibrosis, Duchenne’s dystrophy and many more.